FedEx takes precautionary steps to manage CO2 outgassing in their newest B-777 aircraft
This is a problem that confronts air carriers of temperature-sensitive products, more than the manufacturers themselves, but pharma shippers will have to factor it into their logistics plans in certain circumstances nonetheless. Dry ice—frozen CO2—has been a traditional source of cold to keep temperature-sensitive products at specified temperature (usually, 2-8°C). According to Richard Smith, managing director of the Healthcare Solutions business unit at FedEx (Memphis), the latest generation of Boeing 700-series aircraft (with which FedEx is updating its air-cargo fleet) achieves its higher energy efficiencies, in part, through tight controls on the cabin environment. As a result, if a large shipment of temperature-sensitive pharmaceuticals are being conveyed, and those pharmaceuticals are cooled by dry ice packages, the cabin environment can be affected. There are numerous technical solutions: using phase-change materials or liquid nitrogen for refrigeration, or deploying battery-powered containers with battery-powered refrigeration units; or even limiting the quantity of CO2-containing packages in the shipment. But the upshot is that the quantity of CO2 onboard, and the rate at which it evaporates, needs to be factored into a flight.
Smith, speaking at the Opal Events Pharmaceutical Supply Chain Summit (Baltimore, June 6), also detailed a service that the company is now offering for shipment of controlled room-temperature (CRT) drugs (usually, 15-30°C). Numerous shippers are now deploying engineered thermal blankets around pallets of drug, to protect the shipment from extreme high or low temperatures. Many times, the blanket is considered a disposable item at the end of the shipment. But, by offering blankets FedEx has purchased essentially as a rental service to shippers, and recycling the blankets for new shipments, FedEx can lower the overall shipping expense. FedEx uses blankets from Amsafe, Inc. (Phoenix); Smith says that they have proved especially popular for shipment runs from India to the US.
Protecting Temperature-Sensitive Pharmaceuticals, Without Unnecessary Plastic Waste
March 24th 2025Advances in the life sciences are driving a significant increase in the number of temperature-sensitive pharmaceuticals. The packaging industry is meeting the moment with advances of its own, including high-performance, environmentally-friendly materials that allow life science companies meet stringent thermal requirements and ambitious CO2e reduction goals. In this episode, TemperPack’s CEO Peter Wells shares insights from working with life sciences to move to certified biobased, home compostable, and curbside recyclable shipping solutions.